翻訳と辞書 Words near each other ・ Gene sequencing ・ Gene Serdena ・ Gene set enrichment ・ Gene Settles ・ Gene Severens ・ Gene Shalit ・ Gene Sharp ・ Gene Shay ・ Gene Shearer ・ Gene Sheldon ・ Gene Sherman ・ Gene Sherman (reporter) ・ Gene Sherman (sportscaster) ・ Gene Short ・ Gene Shue ・ Gene signature ・ Gene silencing ・ Gene silencing pesticide ・ Gene Simmons ・ Gene Simmons (album) ・ Gene Simmons Family Jewels ・ Gene Siskel ・ Gene Siskel Film Center ・ Gene Slagle ・ Gene Smith ・ Gene Smith (American football coach) ・ Gene Smith (American football guard) ・ Gene Smith (American football) ・ Gene Smith (athletic director) ・ Gene Smith (Negro leagues pitcher) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Gene signature ： ウィキペディア英語版 Gene signature A gene signature is a group of genes in a cell whose combined expression pattern〔Itadani H, Mizuarai S, Kotani H. Can systems biology understand pathway activation? Gene expression signatures as surrogate markers for understanding the complexity of pathway activation. Curr Genomics. 2008 Aug;9(5):349-60.PMID 19517027〕 is uniquely characteristic of a biological phenotype or medical condition.〔Liu J, Campen A, Huang S, Peng SB, Ye X, Palakal M, Dunker AK, Xia Y, Li S. "Identification of a gene signature in cell cycle pathway for breast cancer prognosis using gene expression profiling data. ''BMC Med Genomics'' 2008 Sep 11;1:39. PMID 18786252〕 The phenotypes that may theoretically be defined by a gene expression signature range from those that are used to differentiate between different subtypes of a disease, those that predict the survival or prognosis of an individual with a disease, to those that predict activation of a particular pathway. Ideally, gene signatures can be used to select a group of patients〔Wouters BJ, Löwenberg B, Erpelinck-Verschueren CA, van Putten WL, Valk PJ, Delwel R. "Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome. ''Blood'' 2009 Mar 26;113(13):3088-91. PMID 19171880〕 for whom a particular treatment will be effective.〔Hassane DC, Guzman ML, Corbett C, Li X, Abboud R, Young F, Liesveld JL, Carroll M, Jordan CT. "Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data. ''Blood'' 2008 Jun 15;111(12):5654-62. Epub 2008 Feb 27.PMID 18305216〕〔Corsello SM, Roti G, Ross KN, Chow KT, Galinsky I, DeAngelo DJ, Stone RM, Kung AL, Golub TR, Stegmaier K. "Identification of AML1-ETO modulators by chemical genomics. ''Blood'' 2009 Jun 11;113(24):6193-205 PMID 19377049〕 == See also == * Genomic signature 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Gene signature」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.